2028281-90-3

2028281-90-3 structure
2028281-90-3 structure
  • Name: t-Boc-Aminooxy-PEG4-CH2CO2H
  • Chemical Name: Boc-Aminooxy-PEG4-CH2CO2H
  • CAS Number: 2028281-90-3
  • Molecular Formula: C15H29NO9
  • Molecular Weight: 367.39
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-16 18:17:13
  • Modify Date: 2024-01-19 17:59:47
  • Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG4-CH2CO2H
Synonyms MFCD30458018
Description Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C15H29NO9
Molecular Weight 367.39
Hazard Codes Xi