Fosphenytoin

Modify Date: 2024-01-02 19:20:05

Fosphenytoin Structure
Fosphenytoin structure
Common Name Fosphenytoin
CAS Number 93390-81-9 Molecular Weight 362.27
Density 1.495g/cm3 Boiling Point N/A
Molecular Formula C16H15N2O6P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fosphenytoin


Fosphenytoin is a phosphate ester prodrug developed as an alternative to intravenous phenytoin for acute intervention of seizures. Fosphenytoin has advantages including more convenient and rapid intravenous administration, availability for intramuscular injection, and low potential for adverse local reactions at injection sites[1].

 Names

Name (2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl dihydrogen phosphate
Synonym More Synonyms

 Fosphenytoin Biological Activity

Description Fosphenytoin is a phosphate ester prodrug developed as an alternative to intravenous phenytoin for acute intervention of seizures. Fosphenytoin has advantages including more convenient and rapid intravenous administration, availability for intramuscular injection, and low potential for adverse local reactions at injection sites[1].
Related Catalog
References

[1]. Fischer JH, et al. Fosphenytoin: clinical pharmacokinetics and comparative advantages in the acute treatment of seizures. Clin Pharmacokinet. 2003;42(1):33-58.

 Chemical & Physical Properties

Density 1.495g/cm3
Molecular Formula C16H15N2O6P
Molecular Weight 362.27
Exact Mass 362.06700
PSA 125.98000
LogP 1.81550
Index of Refraction 1.63

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

fosphenyloin
Fosfenitoina
oxcarbamazepine
3-Phosphoryloxymethyl-diphenylhydantoin
HMPDP
Fosphenytoine
Fosphenytoinum
Prodilantin
Fosphenytoin
3-phosphoryloxymethyl-5,5-diphenylhydantoin