KD5170

Modify Date: 2024-01-14 19:30:34

KD5170 Structure
KD5170 structure
Common Name KD5170
CAS Number 940943-37-3 Molecular Weight 451.56000
Density N/A Boiling Point N/A
Molecular Formula C20H25N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KD5170


KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].

 Names

Name S-(2-{6-[({4-[3-(Dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p yridinyl}-2-oxoethyl) ethanethioate
Synonym More Synonyms

 KD5170 Biological Activity

Description KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].
Related Catalog
References

[1]. Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7(5):1054-65.

 Chemical & Physical Properties

Molecular Formula C20H25N3O5S2
Molecular Weight 451.56000
Exact Mass 451.12400
PSA 139.35000
LogP 3.82910

 Synthetic Route

~27%

KD5170 Structure

KD5170

CAS#:940943-37-3

Literature: KALYPSYS, INC. Patent: WO2008/73733 A1, 2008 ; Location in patent: Page/Page column 45; 47-48 ; WO 2008/073733 A1

 Synonyms

2-PETA
Ethanethioic acid,S-[2-(2-pyridinyl)ethyl] ester
thioacetic acid S-(2-{6-[4-(3-dimethylaminopropoxy)benzenesulfonylamino]pyridin-3-yl}-2-oxoethyl) ester
S-2-(2-pyridyl)ethyl thioacetate
thioacetic acid S-(2-[2]pyridyl-ethyl ester)
2-(2-Acetylthio-ethyl)-pyridin
2-pyridylethyl thioacetate
Thioessigsaeure-S-(2-[2]pyridyl-aethylester)