S-Ruxolitinib
Modify Date: 2024-01-13 19:40:08
S-Ruxolitinib structure
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Common Name | S-Ruxolitinib | ||
|---|---|---|---|---|
| CAS Number | 941685-37-6 | Molecular Weight | 306.365 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 592.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C17H18N6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 312.2±30.1 °C | |
Use of S-RuxolitinibRuxolitinib S enantiomer is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays. |
| Name | S-Ruxolitinib |
|---|---|
| Synonym | More Synonyms |
| Description | Ruxolitinib S enantiomer is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays. |
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| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 592.6±50.0 °C at 760 mmHg |
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.365 |
| Flash Point | 312.2±30.1 °C |
| Exact Mass | 306.159302 |
| PSA | 83.18000 |
| LogP | 1.69 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.747 |
| Storage condition | -20℃ |
| 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βS)- |
| ent-Ruxolitinib |
| (3S)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| Ruxolitinib (S enantiomer) |
| (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile |
| (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| INCB018424 |