Remetinostat

Modify Date: 2024-01-02 18:28:28

Remetinostat Structure
Remetinostat structure
Common Name Remetinostat
CAS Number 946150-57-8 Molecular Weight 323.34100
Density N/A Boiling Point N/A
Molecular Formula C16H21NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Remetinostat


Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].

 Names

Name methyl 4-[8-(hydroxyamino)-8-oxooctanoyl]oxybenzoate
Synonym More Synonyms

 Remetinostat Biological Activity

Description Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].
Related Catalog
Target

HDAC[1].

References

[1]. Yijun Deng, et al. Process Development of the Soft Histone Deacetylate Enzyme Inhibitor SHP-141: Acylation of Methyl Paraben and Suberyl Hydroxamic Acid Formation. Org. Process Res. Dev. 2016, 20, 10, 1812-1820.

 Chemical & Physical Properties

Molecular Formula C16H21NO6
Molecular Weight 323.34100
Exact Mass 323.13700
PSA 101.93000
LogP 2.61550
Storage condition 2-8℃

 Synonyms

Benzoic acid,8-dioxooctyl]oxy]-,methyl ester (MP-shape)
Methylparaben suberohydroxamic acid phenyl ester
Remetinostat