pulcherriminic acid

Modify Date: 2024-01-06 16:05:24

pulcherriminic acid Structure
pulcherriminic acid structure
Common Name pulcherriminic acid
CAS Number 957-86-8 Molecular Weight 256.29800
Density N/A Boiling Point N/A
Molecular Formula C12H20N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pulcherriminic acid


Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries[1][2].

 Names

Name pulcherriminic acid
Synonym More Synonyms

 pulcherriminic acid Biological Activity

Description Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries[1][2].
Related Catalog
In Vitro Pulcherriminic acid can inhibit the formation of Bacillus subtilis biofilm[2]. Pulcherriminic acid can form insoluble red pigment pulcherrimin in the presence of Fe3+ to compete for iron nutrients, thereby inhibiting the growth of Metschnikowia yeasts[3].
References

[1]. Siqi Yuan, et al. Research Progress of the Biosynthesis of Natural Bio-Antibacterial Agent Pulcherriminic Acid in Bacillus. Molecules. 2020 Nov 28;25(23):5611.

[2]. Sofia Arnaouteli, et al. Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13553-13562

[3]. Vytautas Melvydas, et al. In vitro inhibition of Saccharomyces cerevisiae growth by Metschnikowia spp. triggered by fast removal of iron via two ways. Braz J Microbiol. 2020 Dec;51(4):1953-1964. doi: 10.1007/s42770-020-00357-3. Epub 2020 Aug 11.

 Chemical & Physical Properties

Molecular Formula C12H20N2O4
Molecular Weight 256.29800
Exact Mass 256.14200
PSA 87.92000
LogP 1.61670

 Safety Information

HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3,6-diisobutylpyrazine-2,5-diol 1,4-dioxide
1,5-dihydroxy-3,6-bis(2-methylpropyl)-4-oxidopyrazin-4-ium-2-one
Pulcherriminic acid
2,5-Diisobutyl-3,6-dihydroxy-pyrazine-1,4-dioxide