Caspase-3 Substrate

Modify Date: 2024-01-01 18:13:30

Caspase-3 Substrate Structure
Caspase-3 Substrate structure
Common Name Caspase-3 Substrate
CAS Number 958001-92-8 Molecular Weight 674.656
Density 1.4±0.1 g/cm3 Boiling Point 1211.3±65.0 °C at 760 mmHg
Molecular Formula C30H38N6O12 Melting Point N/A
MSDS N/A Flash Point 686.3±34.3 °C

 Use of Caspase-3 Substrate


Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.

 Names

Name N-Acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
Synonym More Synonyms

 Caspase-3 Substrate Biological Activity

Description Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.
In Vitro Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1211.3±65.0 °C at 760 mmHg
Molecular Formula C30H38N6O12
Molecular Weight 674.656
Flash Point 686.3±34.3 °C
Exact Mass 674.254761
LogP 1.29
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.594

 Synonyms

N-Acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
L-α-Asparagine, N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
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