SD 1008
Modify Date: 2024-01-09 12:29:15
SD 1008 structure
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Common Name | SD 1008 | ||
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| CAS Number | 960201-81-4 | Molecular Weight | 329.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H19NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SD 1008SD-1008 is a potent JAK inhibitor. SD-1008 inhibits tyrosyl phosphorylation of STAT3, JAK2 and Src. SD-1008 also reduces STAT3-dependent luciferase activity. SD-1008 enhances apoptosis induced by Paclitaxel in ovarian cancer cells via directly blocking the JAK-STAT3 signaling pathway[1]. |
| Name | Dimethyl (1R,5R,6R,7S)-8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-en e-6,7-dicarboxylate-dimethyl (1S,5S,6S,7R)-8-benzyl-4-oxo-8-aza bicyclo[3.2.1]oct-2-ene-6,7-dicarboxylate (1:1) |
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| Description | SD-1008 is a potent JAK inhibitor. SD-1008 inhibits tyrosyl phosphorylation of STAT3, JAK2 and Src. SD-1008 also reduces STAT3-dependent luciferase activity. SD-1008 enhances apoptosis induced by Paclitaxel in ovarian cancer cells via directly blocking the JAK-STAT3 signaling pathway[1]. |
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| Related Catalog | |
| Target |
JAK2 STAT3 |
| References |
| Molecular Formula | C18H19NO5 |
|---|---|
| Molecular Weight | 329.35 |
| Exact Mass | 658.25300 |
| PSA | 145.82000 |
| LogP | 1.78920 |