(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

Modify Date: 2024-01-02 12:38:08

(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl Structure
(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl structure
Common Name (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
CAS Number 98327-87-8 Molecular Weight 622.67
Density N/A Boiling Point 724.3±55.0 °C at 760 mmHg
Molecular Formula C44H32P2 Melting Point 280-285ºC
MSDS USA Flash Point 419.0±37.8 °C

 Use of (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl


(Rac)-BINAP is the inactive isomer of (R)-BINAP (HY-W017757), and can be used as an experimental control. (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
Synonym More Synonyms

  Biological Activity

Description (Rac)-BINAP is the inactive isomer of (R)-BINAP (HY-W017757), and can be used as an experimental control. (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
References

[1]. Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918.  

 Chemical & Physical Properties

Boiling Point 724.3±55.0 °C at 760 mmHg
Melting Point 280-285ºC
Molecular Formula C44H32P2
Molecular Weight 622.67
Flash Point 419.0±37.8 °C
Exact Mass 622.197937
PSA 27.18000
LogP 13.38
Vapour Pressure 0.0±2.3 mmHg at 25°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles7

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The preparation of bi-functional organophosphine oxides as potential antitumor agents.

Eur. J. Med. Chem. 45 , 5527-30, (2010)

Following our previously reported pyridinyl phosphine oxides as antitumor agents, we targeted the commercially available C(2)-axial chiral organophosphine ligand catalysts, such as 2,2'-bis(diphenylph...

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 Synonyms

L66J CPR&R& B- BL66J CPR&R
2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthalene
Phosphine, 1,1'-[1,1'-binaphthalene]-2,2'-diylbis[1,1-diphenyl-
rac-2,2'-Bis-(diphenylphosphino)-1,1'-binaphthyl
1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane)
(±)-BINAP
1,1'-Binaphthalen-2,2'-diylbis(diphenylphosphan)
1,1'-Binaphthalene-2,2'-diylbis(diphenylphosphine)
rac-binap
1,1'-[1,1'-Binaphthalene]-2,2'-diylbis[1-phenyl-1-(phenylmethyl)phosphine
DL-2,2'-Bis(diphenylphosphino)-1,1'-dinaphthalene
UNII:OX12238KWH
(r)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
BINAP
Phosphine, 1,1'-[1,1'-binaphthalene]-2,2'-diylbis[1-phenyl-1-(phenylmethyl)-
[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]
MFCD00010805
UNII:970O8508MB
1,1'-Binaphthalene-2,2'-diylbis[benzyl(phenyl)phosphine]
UNII:4F1X2F8NA3
(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
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