9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine

Modify Date: 2024-01-06 10:17:47

9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine Structure
9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine structure
Common Name 9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine
CAS Number 98983-40-5 Molecular Weight 270.22
Density 2.01 Boiling Point 744.8ºC at 760 mmHg
Molecular Formula C10H11FN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine


2’-Deoxy-2’-fluoroarabino inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 6H-Purin-6-one,9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-1,9-dihydro
Synonym More Synonyms

  Biological Activity

Description 2’-Deoxy-2’-fluoroarabino inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.01
Boiling Point 744.8ºC at 760 mmHg
Molecular Formula C10H11FN4O4
Molecular Weight 270.22
Exact Mass 270.07600
PSA 113.26000
Index of Refraction 1.81

 Synonyms

9H-Fluorene,9-(2-cyclopropyl-2-propenylidene)
9-(2-cyclopropyl-2-propenylidene)fluorene