γ-terpinene

Modify Date: 2024-01-02 19:05:11

γ-terpinene Structure
γ-terpinene structure
Common Name γ-terpinene
CAS Number 99-85-4 Molecular Weight 136.234
Density 0.8±0.1 g/cm3 Boiling Point 183.0±0.0 °C at 760 mmHg
Molecular Formula C10H16 Melting Point 60-61ºC
MSDS Chinese USA Flash Point 51.7±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Use of γ-terpinene


γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity[1].

 Names

Name γ-terpinene
Synonym More Synonyms

 γ-terpinene Biological Activity

Description γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity[1].
Related Catalog
In Vivo γ-Terpinene (γ-TPN; 12.5, 25 mg/kg; p.o.; single dose) significantly reduces the licking time of the stimulated paw in both phases of the test in male Swiss mice (20-30 g)[1]. γ-Terpinene given either systemically (p.o.; 1.56, 3.125, and 6.25 mg/kg) or centrally (i.t or i.c.v; 10 and 20 μg/site) causes significant inhibition of glutamate-induced nociception in mice[1].
References

[1]. Flávia Franceli de Brito Passos, et al. Involvement of Cholinergic and Opioid System in γ-Terpinene-Mediated Antinociception. Evid Based Complement Alternat Med. 2015;2015:829414.

[2]. Guo-Xiang Li, et al. Unusual antioxidant behavior of alpha- and gamma-terpinene in protecting methyl linoleate, DNA, and erythrocyte. J Agric Food Chem. 2009 May 13;57(9):3943-8.

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 183.0±0.0 °C at 760 mmHg
Melting Point 60-61ºC
Molecular Formula C10H16
Molecular Weight 136.234
Flash Point 51.7±0.0 °C
Exact Mass 136.125198
LogP 4.36
Vapour density 4.7 (vs air)
Vapour Pressure 1.1±0.2 mmHg at 25°C
Index of Refraction 1.476
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OS8070000
CHEMICAL NAME :
p-Mentha-1,4-diene
CAS REGISTRY NUMBER :
99-85-4
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H16
MOLECULAR WEIGHT :
136.26
WISWESSER LINE NOTATION :
L6U CUTJ AY1&1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,875,1976 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,875,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5192 No. of Facilities: 1436 (estimated) No. of Industries: 29 No. of Occupations: 26 No. of Employees: 35259 (estimated) No. of Female Employees: 6925 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R10;R36/37/38
Safety Phrases S26-S36
RIDADR UN 2319 3/PG 3
WGK Germany 2
RTECS OS8070000
Packaging Group III
Hazard Class 3.2
HS Code 2902199090

 Synthetic Route

 Customs

HS Code 2902199090
Summary 2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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 Synonyms

Terpinene
1-Isopropyl-4-methyl-1,4-cyclohexadiene
MFCD00001537
1-methyl-4-propan-2-ylcyclohexa-1,4-diene
gamma-terpinene
1,4-p-Menthadiene
γ-terpinene
1-Methyl-4-isopropyl-1,4-cyclohexadiene
1,4-Cyclohexadiene, 1-methyl-4-(1-methylethyl)-
1-Methyl-4-(propan-2-yl)cyclohexa-1,4-diene
g-Terpinene
p-Mentha-1,4-diene
1-Isopropyl-4-methylcyclohexa-1,4-diene
EINECS 202-794-6
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