Prosaikogenin F

Modify Date: 2024-01-14 17:49:22

Prosaikogenin F Structure
Prosaikogenin F structure
Common Name Prosaikogenin F
CAS Number 99365-20-5 Molecular Weight 618.84
Density N/A Boiling Point N/A
Molecular Formula C36H58O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Prosaikogenin F


Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].

 Names

Name Prosaikogenin F

 Prosaikogenin F Biological Activity

Description Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].
Related Catalog
In Vitro Prosaikogenin F inhibits A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively[1].
In Vivo In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].
References

[1]. Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144.

[2]. M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10.

[3]. M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40.

 Chemical & Physical Properties

Molecular Formula C36H58O8
Molecular Weight 618.84
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