Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Prosaikogenin F
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: Prosaikogenin F
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

99365-20-5

99365-20-5 structure

99365-20-5 structure

Name: Prosaikogenin F
Chemical Name: Prosaikogenin F
CAS Number: 99365-20-5
Molecular Formula: C₃₆H₅₈O₈
Molecular Weight: 618.84
Catalog: Research Areas Cancer
Create Date: 2021-09-09 11:37:54
Modify Date: 2024-01-14 17:49:22
Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].

Name	Prosaikogenin F

Description	Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Prosaikogenin F inhibits A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively[1].
In Vivo	In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].
References	[1]. Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144. [2]. M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10. [3]. M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40.

Molecular Formula	C₃₆H₅₈O₈
Molecular Weight	618.84