Scholaricine

Modify Date: 2024-01-03 21:20:49

Scholaricine structure	Common Name	Scholaricine
	CAS Number	99694-90-3	Molecular Weight	356.42
	Density	1.4±0.1 g/cm3	Boiling Point	519.5±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₄N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	268.0±30.1 °C

Use of Scholaricine

Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].

Name	Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate
Synonym	More Synonyms

Description	Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Shin-Jowl Tan , et al. Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine. J Nat Prod. 2010, 73, 11.

Density	1.4±0.1 g/cm3
Boiling Point	519.5±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₄N₂O₄
Molecular Weight	356.42
Flash Point	268.0±30.1 °C
Exact Mass	356.173615
PSA	82.03000
LogP	1.41
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.684