99694-90-3

99694-90-3 structure

Name: Scholaricine
Chemical Name: Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate
CAS Number: 99694-90-3
Molecular Formula: C₂₀H₂₄N₂O₄
Molecular Weight: 356.42
Catalog: Natural product Alkaloid
Create Date: 2016-02-16 00:05:26
Modify Date: 2024-01-03 21:20:49
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].

Name	Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate
Synonyms	Curan-17-oic acid, 2,16-didehydro-12,19-dihydroxy-, methyl ester, (19S)- Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate

Description	Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Shin-Jowl Tan , et al. Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine. J Nat Prod. 2010, 73, 11.

Hazard Codes	Xi