MAO-B-IN-16

Modify Date: 2024-01-05 19:44:48

MAO-B-IN-16 structure	Common Name	MAO-B-IN-16
	CAS Number	1021238-13-0	Molecular Weight	297.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₉NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MAO-B-IN-16

MAO-B-IN-16 is a selective monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 1.55 µM. MAO-B-IN-16 can be used in the study of central nervous disorders, such as parkinson's disease[1].

Name	MAO-B-IN-16

Description	MAO-B-IN-16 is a selective monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 1.55 µM. MAO-B-IN-16 can be used in the study of central nervous disorders, such as parkinson's disease[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	hMAO-B:1.55 μM (IC50) hMAO-A:＞100 μM (IC50)
In Vitro	MAO-B-IN-16 (compound 4h) (10 μM; 24 h) has no cytotoxic effect on human neuroblastoma cells[1]. Cell Viability Assay[1] Cell Line: SH-SY5Y cells Concentration: 10 μM Incubation Time: 24 h Result: Showed no cytotoxic effect on cells with cellular viability of 99%.
References	[1]. Yamada M, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Medicinal Chemistry Letters, 2022.

Molecular Formula	C₁₈H₁₉NO₃
Molecular Weight	297.35