A1AR antagonist 5

Modify Date: 2024-01-04 16:19:57

Use of A1AR antagonist 5

A1AR antagonist 5 (compound 20) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.83 and a pKi of 6.11[1].

Name	A1AR antagonist 5

Description	A1AR antagonist 5 (compound 20) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.83 and a pKi of 6.11[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	hA1AR:6.11 (pKi) hA2AAR:<4 (pKi)
References	[1]. Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936.

Molecular Formula	C₁₇H₁₅ClN₄O
Molecular Weight	326.78