3′-Azido-2′,3′-dideoxy-5-hydroxyuridine

Modify Date: 2024-01-10 00:20:20

3′-Azido-2′,3′-dideoxy-5-hydroxyuridine Structure
3′-Azido-2′,3′-dideoxy-5-hydroxyuridine structure
Common Name 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine
CAS Number 111495-90-0 Molecular Weight 269.21
Density N/A Boiling Point N/A
Molecular Formula C9H11N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine


3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

Description 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H11N5O5
Molecular Weight 269.21
Exact Mass 269.07600
PSA 154.56000

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

3'-Azido-2',3'-dideoxy-5-hydroxyuridine
Uridine,3'-azido-2',3'-dideoxy-5-hydroxy
3'-N3-5-OH-ddU