3′-Azido-2′,3′-dideoxy-5-hydroxyuridine structure
|
Common Name | 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine | ||
---|---|---|---|---|
CAS Number | 111495-90-0 | Molecular Weight | 269.21 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C9H11N5O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
Name | 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione |
---|---|
Synonym | More Synonyms |
Description | 3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
---|---|
Related Catalog | |
References |
Molecular Formula | C9H11N5O5 |
---|---|
Molecular Weight | 269.21 |
Exact Mass | 269.07600 |
PSA | 154.56000 |
~% 3′-Azido-2′,3′-... CAS#:111495-90-0 |
Literature: Lin, Tai-Shun; Guo, Ji-Yu; Schinazi, Raymond F.; Chu, Chung K.; Xiang, Jia-Ning; Prusoff, Willian H. Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 336 - 340 |
Precursor 1 | |
---|---|
DownStream 1 | |
3'-Azido-2',3'-dideoxy-5-hydroxyuridine |
Uridine,3'-azido-2',3'-dideoxy-5-hydroxy |
3'-N3-5-OH-ddU |