L-Glutamic acid-13C5,d5,15N

Modify Date: 2024-01-05 10:40:24

L-Glutamic acid-13C5,d5,15N Structure
L-Glutamic acid-13C5,d5,15N structure
Common Name L-Glutamic acid-13C5,d5,15N
CAS Number 1420815-74-2 Molecular Weight 158.12
Density N/A Boiling Point N/A
Molecular Formula 13C5H4D515NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Glutamic acid-13C5,d5,15N


L-Glutamic acid-13C5,d5,15N is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

 Names

Name L-Glutamic acid-13C5,d5,15N

 L-Glutamic acid-13C5,d5,15N Biological Activity

Description L-Glutamic acid-13C5,d5,15N is the deuterium, 13C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula 13C5H4D515NO4
Molecular Weight 158.12