Bintrafusp alfa

Modify Date: 2024-04-08 17:13:42

Bintrafusp alfa Structure
Bintrafusp alfa structure
Common Name Bintrafusp alfa
CAS Number 1918149-01-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bintrafusp alfa


Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer[1].

 Names

Name Bintrafusp alfa

 Bintrafusp alfa Biological Activity

Description Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer[1].
Related Catalog
In Vitro Bintrafusp alfa 可以赋予长期保护性免疫,降低调节性 T 细胞功能,显着增加 CD8+ T 细胞和自然杀伤细胞浸润,并减少肿瘤内骨髓来源的抑制细胞浸润[1]。
References

[1]. Strauss J, et, al. Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies. J Immunother Cancer. 2020 Dec;8(2):e001395.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties