Microtubule inhibitor 6

Modify Date: 2024-04-08 11:56:12

Microtubule inhibitor 6 Structure
Microtubule inhibitor 6 structure
Common Name Microtubule inhibitor 6
CAS Number 2416338-64-0 Molecular Weight 434.42
Density N/A Boiling Point N/A
Molecular Formula C24H19FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Microtubule inhibitor 6


Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. Microtubule inhibitor 6 shows cytotoxicity with IC50s of 14.0, 6.6, 7.0 nM for NCI-H460, BxPC-3, HT-29 cells, respectively. Microtubule inhibitor 6 efficiently inhibits microtubule polymerization[1].

 Names

Name Microtubule inhibitor 6

 Microtubule inhibitor 6 Biological Activity

Description Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. Microtubule inhibitor 6 shows cytotoxicity with IC50s of 14.0, 6.6, 7.0 nM for NCI-H460, BxPC-3, HT-29 cells, respectively. Microtubule inhibitor 6 efficiently inhibits microtubule polymerization[1].
Related Catalog
References

[1]. Ding Z, et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

 Chemical & Physical Properties

Molecular Formula C24H19FN2O5
Molecular Weight 434.42