EGFR-IN-67

Modify Date: 2024-01-08 18:27:40

EGFR-IN-67 structure	Common Name	EGFR-IN-67
	CAS Number	2416924-99-5	Molecular Weight	307.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇N₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-67

EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity[1].

Name	EGFR-IN-67

Description	EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:0.34 μM (IC50)
In Vitro	EGFR-IN-67 (Compound 7d) shows cytotoxicity with IC50 values of 4.53 ± 0.28 μM and 39.10 ± 2.37 μM against MCF-7 and WI-38, respectively[1].
References	[1]. George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.

Molecular Formula	C₁₈H₁₇N₃S
Molecular Weight	307.41