COX-1/2-IN-3

Modify Date: 2024-07-18 16:10:20

COX-1/2-IN-3 Structure
COX-1/2-IN-3 structure
Common Name COX-1/2-IN-3
CAS Number 2428387-82-8 Molecular Weight 332.22
Density N/A Boiling Point N/A
Molecular Formula C14H8N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of COX-1/2-IN-3


COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].

 Names

Name COX-1/2-IN-3

 COX-1/2-IN-3 Biological Activity

Description COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].
Related Catalog
Target

COX-1

COX-2

In Vivo COX-1/2-IN-3 (Compound 7a) (1.25 and 0.625 mg/ear) exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity[1].
References

[1]. Gonçalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549.

 Chemical & Physical Properties

Molecular Formula C14H8N2O8
Molecular Weight 332.22