2358849-47-3

2358849-47-3 structure

2358849-47-3 structure

Name: COX-1/2-IN-1
Chemical Name: COX-1/2-IN-1
CAS Number: 2358849-47-3
Molecular Formula: C₁₅H₁₀BrClN₂O
Molecular Weight: 349.61
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2022-05-30 15:04:07
Modify Date: 2024-01-09 14:28:56
COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].

Name	COX-1/2-IN-1

Description	COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1:9.7±0.09 μM (IC50) COX-2:4.6±1.45 μM (IC50)
References	[1]. Malose J. Mphahlele, et al. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides. Medicinal Chemistry Research volume 31, pages146–164 (2022)

Molecular Formula	C₁₅H₁₀BrClN₂O
Molecular Weight	349.61