Antitrypanosomal agent 4

Modify Date: 2024-01-22 16:12:06

Antitrypanosomal agent 4 Structure
Antitrypanosomal agent 4 structure
Common Name Antitrypanosomal agent 4
CAS Number 2456427-48-6 Molecular Weight 419.84
Density N/A Boiling Point N/A
Molecular Formula C18H14ClN3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antitrypanosomal agent 4


Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].

 Names

Name Antitrypanosomal agent 4

 Antitrypanosomal agent 4 Biological Activity

Description Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].
Related Catalog
Target

IC50: 1.2 μM (T. cruzi), 70 nM (T. b. brucei)[1]

References

[1]. Fersing C, Boudot C, Castera-Ducros C, et al. 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi. Eur J Med Chem. 2020;202:112558.

 Chemical & Physical Properties

Molecular Formula C18H14ClN3O5S
Molecular Weight 419.84