Antimycobacterial agent-4

Modify Date: 2024-04-06 17:15:45

Antimycobacterial agent-4 Structure
Antimycobacterial agent-4 structure
Common Name Antimycobacterial agent-4
CAS Number 476319-66-1 Molecular Weight 326.33
Density N/A Boiling Point N/A
Molecular Formula C15H10N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antimycobacterial agent-4


Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].

 Names

Name way-658650

 Antimycobacterial agent-4 Biological Activity

Description Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].
Related Catalog
In Vitro Antimycobacterial agent-4 (compound 12) exerts antimycobacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC99=5 μM), and antiplasmodial activity against the Chloroquine (HY-17589A) sensitive NF54 Plasmodium falciparum strain (IC50=6.1 μM) and cytotoxicity on a mammalian cell line (CHO, IC50=2.2 μM)[1]. Antimycobacterial agent-4 (compound 38) shows cytotoxicity against Vero cells with toxic concentration TC50 of 3.0 μM[2].

 Chemical & Physical Properties

Molecular Formula C15H10N4O3S
Molecular Weight 326.33