Antimycobacterial agent-1

Modify Date: 2024-01-11 18:18:36

Antimycobacterial agent-1 Structure
Antimycobacterial agent-1 structure
Common Name Antimycobacterial agent-1
CAS Number 2409926-02-7 Molecular Weight 396.38
Density N/A Boiling Point N/A
Molecular Formula C18H12N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antimycobacterial agent-1


Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml)[1].

 Names

Name Antimycobacterial agent-1

 Antimycobacterial agent-1 Biological Activity

Description Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml)[1].
Related Catalog
Target

MIC: 1 μg/ml (M. tuberculosis)[1]

References

[1]. Trotsko N, et al. Synthesis and antimycobacterial activity of thiazolidine-2,4-dione based derivatives with halogenbenzohydrazones and pyridinecarbohydrazones substituents. Eur J Med Chem. 2020;189:112045.

 Chemical & Physical Properties

Molecular Formula C18H12N4O5S
Molecular Weight 396.38