522625-85-0
522625-85-0 structure
- Name: Anti-Influenza agent 4
- Chemical Name: Benzamide, N-[3-[[(2-furanylmethyl)amino]sulfonyl]phenyl]-4-methoxy-
- CAS Number: 522625-85-0
- Molecular Formula: C19H18N2O5S
- Molecular Weight: 386.42
- Catalog: Signaling Pathways Anti-infection Influenza Virus
- Create Date: 2022-08-10 19:03:38
- Modify Date: 2024-07-17 16:31:20
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Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1].
| Name | Benzamide, N-[3-[[(2-furanylmethyl)amino]sulfonyl]phenyl]-4-methoxy- |
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| Description | Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1]. |
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| Related Catalog | |
| Target |
EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)[1] |
| In Vitro | Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells[1]. Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively[1]. Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay[1]. Cell Cytotoxicity Assay[1] Cell Line: MDCK cells Concentration: 0-500 μM Incubation Time: 24 and 48 h Result: Exhibited low cytotoxicity with a CC50 value of 450 μM. |
| Molecular Formula | C19H18N2O5S |
|---|---|
| Molecular Weight | 386.42 |
| Storage condition | -20°C |