Tubulin polymerization-IN-30

Modify Date: 2024-01-17 18:16:57

Tubulin polymerization-IN-30 structure	Common Name	Tubulin polymerization-IN-30
	CAS Number	2521560-46-1	Molecular Weight	407.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₅N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin polymerization-IN-30

Tubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC50 values of 2.16, 2.21, and 0.403 μM[1].

Name	Tubulin polymerization-IN-30

Description	Tubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC50 values of 2.16, 2.21, and 0.403 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Wang C, et al. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles. Bioorg Chem. 2020 Nov;104:103909.

Molecular Formula	C₂₂H₂₅N₅O₃
Molecular Weight	407.47

Tubulin polymerization-IN-30

Use of Tubulin polymerization-IN-30

Names

Tubulin polymerization-IN-30 Biological Activity

Chemical & Physical Properties