Nrf2 activator-6 structure
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Common Name | Nrf2 activator-6 | ||
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CAS Number | 2728780-74-1 | Molecular Weight | 614.11 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C31H37ClFN5O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Nrf2 activator-6Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1]. |
Name | Nrf2 activator-6 |
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Description | Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1]. |
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Related Catalog | |
In Vitro | Nrf2 activator-6 (Example 4) 增加 NRF2 介导的基因 NADPH:醌受体氧化还原酶 1 (NQO1) 的 mRNA 水平,EC50 为 0.3 nM[1]。 |
References |
[1]. Cathy Louise LUCAS, et al. Tetrahydroisoquinoline compounds as nrf2 activators. WO2021214470A1. |
Molecular Formula | C31H37ClFN5O5 |
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Molecular Weight | 614.11 |