3’-Azido-3’-deoxy-5-fluorouridine

Modify Date: 2024-01-20 19:19:32

3’-Azido-3’-deoxy-5-fluorouridine Structure
3’-Azido-3’-deoxy-5-fluorouridine structure
Common Name 3’-Azido-3’-deoxy-5-fluorouridine
CAS Number 307520-05-4 Molecular Weight 287.20
Density N/A Boiling Point N/A
Molecular Formula C9H10FN5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Azido-3’-deoxy-5-fluorouridine


3’-Azido-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Azido-3'-deoxy-5-fluorouridine
Synonym More Synonyms

 3’-Azido-3’-deoxy-5-fluorouridine Biological Activity

Description 3’-Azido-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H10FN5O5
Molecular Weight 287.20
Exact Mass 287.066589
LogP -0.74

 Synonyms

3'-Azido-3'-deoxy-5-fluorouridine
Uridine, 3'-azido-3'-deoxy-5-fluoro-