Tanshinone IIA anhydride

Modify Date: 2024-01-09 23:17:23

Tanshinone IIA anhydride Structure
Tanshinone IIA anhydride structure
Common Name Tanshinone IIA anhydride
CAS Number 61077-78-9 Molecular Weight 310.34
Density N/A Boiling Point N/A
Molecular Formula C19H18O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tanshinone IIA anhydride


Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor with Ki values of 1.9 nM and 1.4 nM for human CE1 and the human intestinal CE (hiCE), respectively[1].

 Names

Name Tanshinone IIA anhydride

 Tanshinone IIA anhydride Biological Activity

Description Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor with Ki values of 1.9 nM and 1.4 nM for human CE1 and the human intestinal CE (hiCE), respectively[1].
Related Catalog
Target

Ki: 1.9 nM (Human carboxylesterase (CE)) and 1.4 nM (human intestinal CE)[1]

References

[1]. M Jason Hatfield, et al. Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza ("Danshen"). J Nat Prod. 2018 Nov 26;81(11):2410-2418.  

 Chemical & Physical Properties

Molecular Formula C19H18O4
Molecular Weight 310.34