8-Chloro-2’-O-methyl adenosine

Modify Date: 2024-02-29 14:56:46

8-Chloro-2’-O-methyl adenosine structure	Common Name	8-Chloro-2’-O-methyl adenosine
	CAS Number	634207-55-9	Molecular Weight	315.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₄ClN₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 8-Chloro-2’-O-methyl adenosine

8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,4R,5R)-5-(6-amino-8-chloropurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
Synonym	More Synonyms

Description	8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₁H₁₄ClN₅O₄
Molecular Weight	315.71
Exact Mass	315.07300
PSA	128.54000

Adenosine,8-chloro-2'-O-methyl

8-Chloro-2’-O-methyl adenosine

Use of 8-Chloro-2’-O-methyl adenosine

Names

8-Chloro-2’-O-methyl adenosine Biological Activity

Chemical & Physical Properties

Synonyms