Clindamycin phosphate hydrochloride

Modify Date: 2024-04-03 18:31:20

Clindamycin phosphate hydrochloride structure	Common Name	Clindamycin phosphate hydrochloride
	CAS Number	64023-51-4	Molecular Weight	541.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₅Cl₂N₂O₈PS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Clindamycin phosphate hydrochloride

Clindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the prodrug of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent drug, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis[1][2][3].

Name	Clindamycin phosphate hydrochloride

Description	Clindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the prodrug of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent drug, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Antibiotic, Bacterial[1][3]
References	[1]. Li H, et al. Clindamycin hydrochloride and clindamycin phosphate: two drugs or one? A retrospective analysis of a spontaneous reporting system. Eur J Clin Pharmacol. 2017 Feb;73(2):251-253. [2]. Hayashi N, et al. Clindamycin phosphate 1.2%/benzoyl peroxide 3% fixed-dose combination gel versus topical combination therapy of adapalene 0.1% gel and clindamycin phosphate 1.2% gel in the treatment of acne vulgaris in Japanese patients: A multicenter, randomized, investigator-blind, parallel-group study. J Dermatol. 2018 Aug;45(8):951-962. [3]. A. Dupre, et al. Proof of concept study of a novel bioadhesive clindamycin phosphate 2% vaginal gel to treat bacterial vaginosis. Clin. Exp. Obstet. Gynecol. 2020, 47(4), 516–518

Molecular Formula	C₁₈H₃₅Cl₂N₂O₈PS
Molecular Weight	541.42

Clindamycin phosphate hydrochloride

Use of Clindamycin phosphate hydrochloride

Names

Clindamycin phosphate hydrochloride Biological Activity

Chemical & Physical Properties