MK-4965
Modify Date: 2024-01-03 15:52:34
MK-4965 structure
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Common Name | MK-4965 | ||
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| CAS Number | 920035-77-4 | Molecular Weight | 426.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H13Cl2N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-4965MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI). MK-4965 displays excellent activities against not only HIV-1 wild-type (WT) virus but also against a broad panel of NNRTI-resistant viruses and can be used for the research of HIV-1 infection[1]. |
| Name | 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloroph enoxy}-5-chlorobenzonitrile |
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| Description | MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI). MK-4965 displays excellent activities against not only HIV-1 wild-type (WT) virus but also against a broad panel of NNRTI-resistant viruses and can be used for the research of HIV-1 infection[1]. |
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| Related Catalog | |
| Target |
IC50: 0.23 nM (WT), 0.39 nM (Y181C), 0.40 nM (K103N)[1] |
| References |
| Molecular Formula | C20H13Cl2N5O2 |
|---|---|
| Molecular Weight | 426.26 |
| Exact Mass | 425.04500 |
| PSA | 110.57000 |
| LogP | 5.01998 |