NPPB
NPPB结构式
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常用名 | NPPB | 英文名 | NPPB |
|---|---|---|---|---|
| CAS号 | 107254-86-4 | 分子量 | 300.30900 | |
| 密度 | 1.323 g/cm3 | 沸点 | 523.5ºC at 760 mmHg | |
| 分子式 | C16H16N2O4 | 熔点 | 178-179ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Ion channel expression in the developing enteric nervous system.
PLoS ONE 10(3) , e0123436, (2015) The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemistry. Many ... |
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Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats.
Mol. Pain 11 , 41, (2015) Calcium-activated chloride channels (CaCCs) activation induces membrane depolarization by increasing chloride efflux in primary sensory neurons that can facilitate action potential generation. Previous studies suggest that CaCCs family members bestrophin-1 an... |
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Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns.
Cell Death Dis. 5 , e1494, (2014) Apoptosis, which is anti-inflammatory, and necrosis, which is pro-inflammatory, represent the extremes of the cell death spectrum. Cell death is complex and both apoptosis and necrosis can be observed in the same cells or tissues. Here, we introduce a novel c... |
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Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods.
Am. J. Physiol. Cell Physiol. 308 , C1008-22, (2015) GLUT12 is a member of the facilitative family of glucose transporters. The goal of this study was to characterize the functional properties of GLUT12, expressed in Xenopus laevis oocytes, using radiotracer and electrophysiological methods. Our results showed ... |
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Anoctamin-1 in the juvenile rat urinary bladder.
PLoS ONE 9(9) , e106190, (2014) To investigate presence, location and functional role of calcium-activated chloride channel (CaCC) Anoctamin-1 (Ano1) in rat urinary bladder.Bladders from 3 week old Wistar rats were studied. End-point PCR on total mRNA was used to assess the expression of An... |
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Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance.
Biochem. Pharmacol. 93(3) , 305-17, (2015) Curcumin (CUR) is a phytochemical that inhibits the xenobiotic ABC efflux transporters implicated in cancer multidrug resistance (MDR), such as P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins 1 and 5... |
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Cystic fibrosis transmembrane conductance regulator is involved in polyphenol-induced swelling of the endothelial glycocalyx.
Nanomedicine: Nanotechnology, Biology, and Medicine 11 , 1521-30, (2015) Previous studies show that polyphenol-rich compounds can induce a swelling of the endothelial glycocalyx (eGC). Our goal was to reveal the mechanism behind the eGC-swelling. As polyphenols are potent modulators of fibrosis transmembrane conductance regulator ... |
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Intracellular Ca(2+) release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal.
Am. J. Physiol. Cell Physiol. 308 , C608-20, (2015) Interstitial cells of Cajal (ICC) provide pacemaker activity in gastrointestinal muscles that underlies segmental and peristaltic contractions. ICC generate electrical slow waves that are due to large-amplitude inward currents resulting from anoctamin 1 (ANO1... |
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Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum.
PLoS ONE 9(5) , e96216, (2014) In human erythrocytes (h-RBCs) various stimuli induce increases in [cAMP] that trigger ATP release. The resulting pattern of extracellular ATP accumulation (ATPe kinetics) depends on both ATP release and ATPe degradation by ectoATPase activity. In this study ... |
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Uterine Contractility in the Nonpregnant Mouse: Changes During the Estrous Cycle and Effects of Chloride Channel Blockade.
Biol. Reprod. 92 , 141, (2015) Mechanisms involved in the generation of spontaneous uterine contractions are not fully understood. Kit-expressing interstitial cells of Cajal are pacemakers of contractile rhythm in other visceral organs, and recent studies describe a role for Ca(2+)-activat... |