N,N-二甲基苄胺

N,N-二甲基苄胺用途

用途一:用作有机合成中间体，还可用作脱氢催化剂、防腐剂、酸中和剂等
用途二:用于有机合成
用途三:有机合成中间体，用于生产新洁而灭脱氢卤的催化剂、阻蚀剂、酸性中和剂、电子显微镜切片包埋用加速剂
用途四:本产品为有机合成中间体，如合成季铵盐等，还用于脱氢催化剂，防腐剂，酸的中和剂等
用途五:18-甲基炔诺酮，三烯高诺酮的中间体，甾体化合物全合成中D环的前体

N,N-二甲基苄胺名称

[ CAS 号 ]:
103-83-3

[ 中文名 ]:
N,N-二甲基苄胺

[ 英文名 ]:
dimethylbenzylamine

[中文别名 ]:

[英文别名 ]:

dimethylbenzylamine
N,N-Dimethylbenzylam
N-BENZYLDIETHYLAMINE
Pentamin BDMA etc
Benzyldimethylamine
BENZYLDIETHYLAMINE
Dabco B-16
dimethylaminomethylbenzene
BDMA
EINECS 203-149-1

N,N-二甲基苄胺物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
181.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-75 °C

[ 分子式 ]:
C₉H₁₃N

[ 分子量 ]:
135.206

[ 闪点 ]:
54.4±0.0 °C

[ 精确质量 ]:
135.104797

[ PSA ]:
3.24000

[ LogP ]:
1.98

[ 外观性状 ]:
一种无色至淡黄色液体带有一种氨气味

[ 蒸汽压 ]:
0.9±0.3 mmHg at 25°C

[ 折射率 ]:
1.517

[ 储存条件 ]:
库房通风低温干燥,与酸分开存放

[ 稳定性 ]:
Stable. Incompatible with strong acids, strong oxidizing agents.

[ 水溶解性 ]:
8 g/L (20 ºC)

N,N-二甲基苄胺MSDS

N,N-二甲基苄胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DP4500000

CHEMICAL NAME :: Benzylamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 103-83-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C9-H13-N

MOLECULAR WEIGHT :: 135.23

WISWESSER LINE NOTATION :: 1N1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 8,43,1985

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 8,43,1985 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 265 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KorCJ# Personal Communication from C.J. Korpics, Sherwin-Williams Chemicals, 1310 Expressway Drive,t/ Toledo, OH 43608, Aug. 22, 1974 Volume(issue)/page/year: 22AUG1974

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/m3/2H

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 5,6,1963

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 mg/m3/2H

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 5,6,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1660 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - excitement

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 8,43,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 mg/m3/4H/26W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Kidney, Ureter, Bladder - other changes in urine composition

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 5,6,1963 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83034 No. of Facilities: 142 (estimated) No. of Industries: 5 No. of Occupations: 34 No. of Employees: 23940 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83034 No. of Facilities: 110 (estimated) No. of Industries: 8 No. of Occupations: 8 No. of Employees: 2150 (estimated) No. of Female Employees: 249 (estimated)

N,N-二甲基苄胺安全信息

[ 符号 ]:

GHS02, GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H302 + H312 + H332-H314-H412

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R10;R20/21/22;R34;R52/53

[ 安全声明 (欧洲) ]:
S26-S36-S45-S61

[ 危险品运输编码 ]:
UN 2619 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
DP4500000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
2921499090

N,N-二甲基苄胺合成路线

N,N-二甲基苄胺上下游产品

N,N-二甲基苄胺上游产品

N,N-二甲基苄胺下游产品

N,N-二甲基苄胺制备

（1）苄和二甲胺反应而得。先向反应锅中加入二甲胺，搅拌下加入氯化苄，温度控制在25℃以下。滴加完毕，在室温下搅拌反应1h，再慢慢升高温度至55-60℃继续反应6h。然后加入液碱静置分层，取油层，用热水洗涤，减压蒸馏，收集67-72℃（1.87kpa）馏分，得苄基二甲胺。原料消耗：二甲胺2666kg/t;氯化苄860kg/t。（2）向反应釜中投入二甲胺100kg，在搅拌及水浴冷却条件下缓慢滴加115kg氯化苄，滴加完毕撤去冷却水，常温下反应2h,再用蒸汽加热至50-60℃，反应5h。反应结束后将釜中的水放掉，再用热水洗涤两次，水洗后停止搅拌，用循环水冷却，40h后将水放掉。收集料相即可得到粗品。将粗产品减压蒸馏，收集1.6kpa下、气相温度70-72℃的馏分，即可得到化学纯的N，N-二甲基苄胺。

N,N-二甲基苄胺海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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