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磺胺苯甲酰

磺胺苯甲酰用途

【用途一】
本品对葡萄球菌 ,绿脓杆菌,变形杆菌有抑制作用与ST SA 联合应用可使抑菌效力大大加强.

磺胺苯甲酰名称

[ CAS 号 ]:
127-71-9

[ 中文名 ]:
苯甲酰磺胺

[ 英文名 ]:
Sulfabenzamide

[中文别名 ]:

[英文别名 ]:

Benzamide, N-[(4-aminophenyl)sulfonyl]-
N-[(4-Aminophenyl)sulfonyl]benzamide
N-(4-Aminobenzenesulfonyl)benzamide
4-Amino-N-benzoylbenzenesulfonamide
N-Benzoylsulfanilamide
Sulfabenzamide
N-(4-aminophenyl)sulfonylbenzamide
MFCD00044890
Sulfabenzamide(SB)
Sultrin

磺胺苯甲酰生物活性

[ 描述 ]:

Sulfabenzamide 是一种有机合成和医药中间体。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

研究领域 >> 其他

[相关活性小分子]

磺胺苯甲酰物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 熔点 ]:
180-184 °C

[ 分子式 ]:
C₁₃H₁₂N₂O₃S

[ 分子量 ]:
276.311

[ 精确质量 ]:
276.056854

[ PSA ]:
97.64000

[ LogP ]:
1.19

[ 外观性状 ]:
白色至灰白色固体

[ 折射率 ]:
1.636

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
0.3 g/L (20 ºC)

磺胺苯甲酰MSDS

详细MSDS(安全技术说明书)

磺胺苯甲酰毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5802500

CHEMICAL NAME :: Benzamide, N-sulfanilyl-

CAS REGISTRY NUMBER :: 127-71-9

BEILSTEIN REFERENCE NO. :: 2139003

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H12-N2-O3-S

MOLECULAR WEIGHT :: 276.33

WISWESSER LINE NOTATION :: ZR DSWMVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03348

磺胺苯甲酰安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
N

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
3249

[ WGK德国 ]:
3

[ RTECS号 ]:
CV5802500

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2934999090

磺胺苯甲酰合成路线

详细合成路线

磺胺苯甲酰上下游产品

磺胺苯甲酰上游产品

磺胺苯甲酰下游产品

磺胺苯甲酰海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

磺胺苯甲酰文献

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...

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