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Ac-DEVD-pNA

Ac-DEVD-pNA用途

Ac-DEVD-pNA 是 caspase-3 和相关半胱氨酸蛋白酶的配体。

Ac-DEVD-pNA名称

[ CAS 号 ]:
189950-66-1

[ 中文名 ]:
AC-ASP-GLU-VAL-ASP-PNA

[ 英文名 ]:
Ac-Asp-Glu-Val-Asp-pNA

[中文别名 ]:

[英文别名 ]:

AC-DEVD-PNA
MFCD00792707

Ac-DEVD-pNA生物活性

[ 描述 ]:

Ac-DEVD-pNA 是 caspase-3 和相关半胱氨酸蛋白酶的配体。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

多肽产品

[参考文献]

[1]. Talanian RV, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997 Apr 11;272(15):9677-82.

[相关活性小分子]

Ac-DEVD-pNA物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
1187.0±65.0 °C at 760 mmHg

[ 分子式 ]:
C₂₆H₃₄N₆O₁₃

[ 分子量 ]:
638.581

[ 闪点 ]:
671.6±34.3 °C

[ 精确质量 ]:
638.218384

[ PSA ]:
303.22000

[ LogP ]:
1.09

[ 外观性状 ]:
白色

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.593

[ 储存条件 ]:
-20°C

Ac-DEVD-pNAMSDS

详细MSDS(安全技术说明书)

Ac-DEVD-pNA安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Ac-DEVD-pNA文献

Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling

J. Steroid Biochem. Mol. Biol. 144 Pt B , 334-47, (2014)

• Age-dependent action of nonylphenol (NP) on mouse neuronal cells was demonstrated. • Estrogen receptor (ER) antagonists potentiated the NP-induced apoptosis and toxicity. • ER agonists inhibited the...

The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production.

Biochem. Biophys. Res. Commun. 463 , 545-50, (2015)

In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide...

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts.

Biochim. Biophys. Acta 1842(12 Pt A) , 2468-78, (2014)

The cardiotoxicity induced by the anti-cancer doxorubicin involves increased oxidative stress, disruption of calcium homeostasis and activation of cardiomyocyte death. Nevertheless, antioxidants and c...

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