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2-羟基-2-甲基丁酸

2-羟基-2-甲基丁酸用途

2-Hydroxy-2-methylbutanoic acid 是一种非正常的代谢物,和羟基戊二酸尿症以及枫糖尿病有关。

2-羟基-2-甲基丁酸名称

[ CAS 号 ]:
3739-30-8

[ 中文名 ]:
2-羟基-2-甲基丁酸

[ 英文名 ]:
2-Hydroxy-2-methylbutyric acid

[中文别名 ]:

[英文别名 ]:

2-hydroxy-2-methyl-butyric acid
2-Hydroxy-2-methyl-n-butyric acid
2-Hydroxy-2-methylbutyric acid
EINECS 223-120-7
2-Hydroxy-2-methylbutanoic acid
Butanoic acid, 2-hydroxy-2-methyl-
2-hydroxy-2-methyl-butanoic acid
MFCD00004476

2-羟基-2-甲基丁酸生物活性

[ 描述 ]:

2-Hydroxy-2-methylbutanoic acid 是一种非正常的代谢物,和羟基戊二酸尿症以及枫糖尿病有关。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Dekant W, et al. Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans. Res Rep Health Eff Inst. 2001 May;(102):29-71; discussion 95-109.

[相关活性小分子]

2-羟基-2-甲基丁酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
237.6±13.0 °C at 760 mmHg

[ 熔点 ]:
73-75 °C(lit.)

[ 分子式 ]:
C₅H₁₀O₃

[ 分子量 ]:
118.131

[ 闪点 ]:
111.8±16.3 °C

[ 精确质量 ]:
118.062996

[ PSA ]:
57.53000

[ LogP ]:
0.18

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.460

[ 储存条件 ]:
室温，干燥

2-羟基-2-甲基丁酸MSDS

详细MSDS(安全技术说明书)

2-羟基-2-甲基丁酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2918199090

2-羟基-2-甲基丁酸上下游产品

2-羟基-2-甲基丁酸上游产品

2-羟基-2-甲基丁酸下游产品

2-羟基-2-甲基丁酸制备

1. 烟草：BU，26。

2-羟基-2-甲基丁酸海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2-羟基-2-甲基丁酸文献

Commercial formaldehyde standard for mass calibration in mass spectrometry.

J. Mass Spectrom. 50(3) , 463-9, (2015)

Common calibration standards for mass spectrometry can be a source of many problems including instrument contamination, ionization suppression and formation of unidentified ions during subsequent anal...

Biotransformation and kinetics of excretion of tert-amyl-methyl ether in humans and rats after inhalation exposure.

Toxicol. Sci. 55(2) , 274-83, (2000)

tert-Amyl methyl ether (TAME) may be widely used as an additive to gasoline in the future. The presence of this ether in gasoline reduces the tail pipe emission of pollutants. Therefore, widespread hu...

Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids.

J. Chromatogr. B. Biomed. Sci. Appl. 758(1) , 87-94, (2001)

There are several organic acid disorders that require information on alpha-ketoacids, such as maple syrup urine disease or alpha-ketoadipic acidemia. The recovery, stability and diagnostic availabilit...

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