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氯丙那林

氯丙那林用途

氯丙瑞林是β2-肾上腺素能受体激动剂。氯丙瑞林促进动物肌肉的生长,减少脂肪的积累。Clorprenaline是一种潜在的新型瘦肉增强饲料添加剂[1]。

氯丙那林名称

[ CAS 号 ]:
3811-25-4

[ 中文名 ]:
氯丙那林

[ 英文名 ]:
Clorprenaline

[中文别名 ]:

[英文别名 ]:

Isoprophenamine
Clorprenaline HCl
1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol
Clorprenalinum
Chlorprenalin
Isoprophenamine (VAN)
Isoprophenamin
1-(2-Chlorophenyl)-2-(isopropylamino)ethanol
o-Chloro-α-((isopropylamino)methyl)benzyl alcohol
EINECS 223-291-8

氯丙那林生物活性

[ 描述 ]:

氯丙瑞林是β2-肾上腺素能受体激动剂。氯丙瑞林促进动物肌肉的生长,减少脂肪的积累。Clorprenaline是一种潜在的新型瘦肉增强饲料添加剂[1]。

[ 相关类别 ]:

研究领域 >> 内分泌

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体

[ 靶点 ]

β2-adrenergic[1]

[参考文献]

[1]. Peng T, et al. Lateral-flow assay for rapid quantitative detection of clorprenaline residue in swine urine. J Food Prot. 2014;77(10):1824-1829.

氯丙那林物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
329.7±27.0 °C at 760 mmHg

[ 分子式 ]:
C₁₁H₁₆ClNO

[ 分子量 ]:
213.704

[ 闪点 ]:
153.2±23.7 °C

[ 精确质量 ]:
213.092041

[ PSA ]:
32.26000

[ LogP ]:
2.18

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.537

[ 储存条件 ]:
室温，干燥，密封

氯丙那林安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22-36

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2922199090

氯丙那林合成路线

详细合成路线

氯丙那林上下游产品

氯丙那林上游产品

氯丙那林下游产品

氯丙那林制备

【方法一】
α-溴代邻氯苯乙酮用钾硼氢还原为1-邻氯苯基-2-溴代乙醇，与异丙胺进行胺化得到1-邻氯苯基-2-异丙胺基乙醇，即氯喘碱基，成盐后即为氯喘盐酸盐。

氯丙那林海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

氯丙那林文献

Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis.

Electrophoresis 29(11) , 2321-9, (2008)

The analysis is described for separating seven beta-adrenergic blocking agents (atenolol, celiprolol, clorprenaline, fenoterol, metoprolol, propranolol, terbutaline) and clenbuterol (sympathomimetic b...

[Studies on sustained-release dosage forms for clorprenaline pamoate].

Yao Xue Xue Bao 17(6) , 469-71, (1982)

[Simultaneous determination of three components in compound clorprenaline tablet by using the derivative-complementary tristimulus method].

Yao Xue Xue Bao 25(5) , 357-61, (1990)

Clorprenaline hydrochloride (a), bromhexine hydrochloride (b) and decloxizine hydrochloride (c) are three main components in clorprenaline compound tablet. The serious overlapping bands of their absor...

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