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草酰二胺

草酰二胺用途

【用途一】
用作硝化纤维制品的稳定剂。也可用作缓效肥料。在推进剂中用作降速剂，在衬层配方中用作增链增黏剂，在燃气发生剂中用作发气剂和降温剂。

草酰二胺名称

[ CAS 号 ]:
471-46-5

[ 中文名 ]:
草酰胺

[ 英文名 ]:
oxamide

[中文别名 ]:

[英文别名 ]:

Oxalic acid diamide
Diaminoglyoxal
Oxamid
Formimidic acid,1-carbamoyl
Ethanediamide
ethanimidic acid, 2-amino-2-oxo-
Oxamide
MFCD00008007
Oxamimidic acid
EINECS 207-442-5

草酰二胺物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
262.7±23.0 °C at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₂H₄N₂O₂

[ 分子量 ]:
88.065

[ 闪点 ]:
112.7±22.6 °C

[ 精确质量 ]:
88.027275

[ PSA ]:
86.18000

[ LogP ]:
-1.96

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.496

[ 储存条件 ]:
室温

[ 水溶解性 ]:
insoluble

草酰二胺MSDS

草酰二胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RO4900000

CHEMICAL NAME :: Oxamide

CAS REGISTRY NUMBER :: 471-46-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C2-H4-N2-O2

MOLECULAR WEIGHT :: 88.08

WISWESSER LINE NOTATION :: ZVVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,339,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,10,1953

草酰二胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ RTECS号 ]:
RO4900000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
29241900

草酰二胺合成路线

草酰二胺上下游产品

草酰二胺上游产品

草酰二胺下游产品

草酰二胺海关

[ 海关编码 ]: 29241900

草酰二胺文献

Uses of 1-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]-thiophen-2-yl)-3-dodecanoylthiourea as a Building Block in the Synthesis of Fused Pyrimidine and Thiazine Systems.

Chem. Pharm. Bull. 63 , 450-6, (2015)

The reaction of lauroyl isothiocyanate and 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile was used to synthesize the title compound 2. Compound 2 could serve as the main building block in ...

Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

Am. J. Pathol. 185(4) , 969-86, (2015)

Myofibroblasts are crucial to the pathogenesis of tissue fibrosis. Their formation of stress fibers results in the release of myocardin-related transcription factor (MRTF), a transcriptional coactivat...

Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes.

J. Enzyme Inhib. Med. Chem. 17(1) , 1-7, (2002)

Schiff bases derived from oxaldiamide/oxalylhydrazine and pyrrol-2-carbaldehyde, or salicylaldehyde respectively, as well as their Zn(II) complexes have been prepared and tested as antibacterial agent...

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