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牛奶树碱

牛奶树碱用途

Hispidin 是一种 PKC 抑制剂,是一种产自 Phellinus linteus 的酚类化合物,具有很强的抗氧化、抗癌、抗糖尿病和抗痴呆作用。

牛奶树碱名称

[ CAS 号 ]:
555-55-5

[ 中文名 ]:
牛奶树碱

[ 英文名 ]:
HISPIDIN

[中文别名 ]:

6-(3,4-二羟基苯乙烯)-4-羟基-2-芘酮

[英文别名 ]:

6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone

牛奶树碱生物活性

[ 描述 ]:

Hispidin 是一种 PKC 抑制剂,是一种产自 Phellinus linteus 的酚类化合物,具有很强的抗氧化、抗癌、抗糖尿病和抗痴呆作用。

[ 相关类别 ]:

信号通路 >> 表观遗传学 >> PKC

研究领域 >> 心血管疾病

研究领域 >> 代谢疾病

信号通路 >> TGF-beta/Smad 信号通路 >> PKC

[参考文献]

[1]. Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.

牛奶树碱物理化学性质

[ 密度 ]:
1.657g/cm3

[ 沸点 ]:
554.2ºC at 760 mmHg

[ 熔点 ]:
312-315ºC

[ 分子式 ]:
C₁₃H₁₀O₅

[ 分子量 ]:
246.21500

[ 闪点 ]:
220.1ºC

[ 精确质量 ]:
246.05300

[ PSA ]:
90.90000

[ LogP ]:
1.92700

[ 外观性状 ]:
固体;Light yellow to Brown powder to crystal

[ 折射率 ]:
1.854

[ 储存条件 ]:
-20°C;避免光,加热

牛奶树碱MSDS

详细MSDS(安全技术说明书)

牛奶树碱安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

牛奶树碱文献

Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-κB activation.

J. Sci. Food Agric. 95 , 2482-6, (2015)

Hispidin, a polyphenol compound mainly derived from the valuable medicinal mushroom Phellinus species, has been found to possess distinct biological effects. However, the anti-inflammatory potential o...

Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells.

Anticancer Res. 34(8) , 4087-93, (2014)

Few studies have been performed on the anticancer activity of hispidin, a phenolic compound produced from the medicinal mushroom Phellinus linteus. Herein, we studied hispidin-induced apoptosis, which...

The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.

Exp. Cell Res. 327(2) , 264-75, (2014)

Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardi...

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