三癸精

三癸精用途

Tricaprin (Glyceryl tridecanoate) 是癸酸的口服可用前体 (DA precursor),可被水解为癸酸。Tricaprin (Glyceryl tridecanoate)是中链甘油三酸酯 (MCT) 的主要成分,具有抗雄激素和抗高血糖特性。 Tricaprin (Glyceryl tridecanoate) 可以用做食品,药品,化妆品中的添加剂。

三癸精名称

[ CAS 号 ]:
621-71-6

[ 中文名 ]:
三癸酸甘油酯

[ 英文名 ]:
Tricaprin

[中文别名 ]:

[英文别名 ]:

Glycerin tricaprate
Propane-1,2,3-triyl tridecanoate
Capric triglyceride
Glycerin tridecanoate
Tridecanoin
EINECS 210-702-0
Tridécanoate de 1,2,3-propanetriyle
1,2,3-Tridecanoylglycerol
MFCD00036239
Tricaprin

三癸精生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Tricaprin (Code C153424)

三癸精物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
578.6±17.0 °C at 760 mmHg

[ 熔点 ]:
31-32 °C

[ 分子式 ]:
C₃₃H₆₂O₆

[ 分子量 ]:
554.842

[ 闪点 ]:
233.3±21.0 °C

[ 精确质量 ]:
554.454651

[ PSA ]:
78.90000

[ LogP ]:
12.52

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.461

[ 储存条件 ]:
−20°C

三癸精MSDS

三癸精毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HE0100000

CHEMICAL NAME :: Decanoic acid, 1,2,3-propanetriyl ester

CAS REGISTRY NUMBER :: 621-71-6

BEILSTEIN REFERENCE NO. :: 1717683

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C33-H62-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APSCAX Acta Physiologica Scandinavica. (Karolinska Institutet, S-10401 Stockholm, Sweden) V.1- 1940- Volume(issue)/page/year: 40,338,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1246 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1288 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1246 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1076 (estimated) No. of Female Employees: 980 (estimated)

三癸精安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H302 + H312 + H332-H315-H319

[ 警示性声明 ]:
P210-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
F,Xn

[ 风险声明 (欧洲) ]:
R11

[ 安全声明 (欧洲) ]:
S26-S28

[ 危险品运输编码 ]:
UN 1282 3/PG 2

[ WGK德国 ]:
-

[ RTECS号 ]:
HE0100000

[ 海关编码 ]:
3824909990

三癸精合成路线

三癸精上下游产品

三癸精上游产品

三癸精下游产品

三癸精海关

[ 海关编码 ]: 3824909990

三癸精文献

Chain length affects pancreatic lipase activity and the extent and pH-time profile of triglyceride lipolysis.

Eur. J. Pharm. Biopharm. 93 , 353-62, (2015)

Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered dr...

Surface properties of artificial tear film lipid layers: effects of wax esters.

Invest. Ophthalmol. Vis. Sci. 55(7) , 4448-54, (2014)

The tear film lipid layer is believed to stabilize the tear film and to retard evaporation. Based on previous simple in vitro studies, the evidence for the latter property is scarce. In this study, we...

Effect of additives on the release of a model protein from PLGA microspheres.

AAPS PharmSciTech 2(4) , 30, (2001)

The purpose of this study was to investigate the effect of 2 additives, poly(ethylene glycol) (PEG) 1000 and 1,2,3-tridecanoyl glycerol (tricaprin), on the physico-chemical characteristics and in vitr...

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三癸精