恩前列素
恩前列素用途
恩前列素名称
[ CAS 号 ]:
73121-56-9
[ 中文名 ]:
恩前列素
[ 英文名 ]:
Enprostil
[中文别名 ]:
[英文别名 ]:
- Enprostil (JAN/USAN/INN)
- Syngard
- Enprostil
- Camleed (TN)
- Gardrine
- Camleed
- Gardrin
恩前列素生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
恩前列素物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
552.9±50.0 °C at 760 mmHg
[ 分子式 ]:
C23H28O6
[ 分子量 ]:
400.46
[ 闪点 ]:
185.7±23.6 °C
[ 精确质量 ]:
400.188599
[ PSA ]:
93.06000
[ LogP ]:
1.45
[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C
[ 折射率 ]:
1.586
恩前列素毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MI5433000
- CHEMICAL NAME :
- 4,5-Heptadienoic acid, 7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxoc yclopentyl)-, methyl ester, (1-alpha,2-beta(1E,3R*),3-alpha)-
- CAS REGISTRY NUMBER :
- 73121-56-9
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C23-H28-O6
- MOLECULAR WEIGHT :
- 400.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1600 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis Musculoskeletal - other changes Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,2327,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >160 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,2327,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,2327,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - tremor Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,2327,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- >320 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,2327,1989
恩前列素合成路线
恩前列素上下游产品
恩前列素上游产品
恩前列素下游产品
恩前列素制备
化合物(Ⅰ)先经硅烷化,再氧化,然后脱硅烷基,得到恩前列素。
相关药品:
推荐生产厂家/供应商:
相关化合物
【恩前列素】化源网提供恩前列素CAS号73121-56-9,恩前列素MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询恩前列素上化源网,专业又轻松。>>电脑版:恩前列素
标题:恩前列素_用途_密度_沸点_恩前列素CAS号【73121-56-9】_化源网 地址:https://www.chemsrc.com/amp/cas/73121-56-9_897205.html