L(-)-葑酮

L(-)-葑酮用途

(-)-Fenchone 是一种双环单萜类化合物,广泛分布于植物中,并存在于西洋柏的精油中。在肝微粒体中,CYP2A6 和 CYP2B6 氧化 (-)-Fenchone 为 6-endo-hydroxyfenchone,6-exo-hydroxyfenchone 和 10-hydroxyfenchone 衍生物。

L(-)-葑酮名称

[ CAS 号 ]:
7787-20-4

[ 中文名 ]:
(1R)-1,3,3-三甲基二环[2.2.1]庚-2-酮

[ 英文名 ]:
(-)-Fenchone

[中文别名 ]:

[英文别名 ]:

(1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-one
EINECS 232-107-5
MFCD00151104
(1R)-(-)-Fenchone
2-Norbornanone, 1,3,3-trimethyl-, (1R,4S)-(+)-
(-)-1,3,3-Trimethyl-2-norbornanone
(+)-FENCHONE
(1R,4S)-fenchone

L(-)-葑酮生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Miyazawa M, et al. Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes. Xenobiotica. 2007;37(2):194-204.

L(-)-葑酮物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
193.5±0.0 °C at 760 mmHg

[ 熔点 ]:
5ºC

[ 分子式 ]:
C₁₀H₁₆O

[ 分子量 ]:
152.233

[ 闪点 ]:
52.8±0.0 °C

[ 精确质量 ]:
152.120117

[ PSA ]:
17.07000

[ LogP ]:
2.13

[ 蒸汽压 ]:
0.5±0.3 mmHg at 25°C

[ 折射率 ]:
1.485

[ 储存条件 ]:
Flammables area

L(-)-葑酮MSDS

L(-)-葑酮安全信息

[ 符号 ]:

GHS02

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 风险声明 (欧洲) ]:
R10

[ 安全声明 (欧洲) ]:
S16

[ 危险品运输编码 ]:
UN 1224 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
RB7875000

[ 包装等级 ]:
III

[ 危险类别 ]:
3.0

L(-)-葑酮合成路线

L(-)-葑酮上下游产品

L(-)-葑酮上游产品

L(-)-葑酮下游产品

L(-)-葑酮制备

由茴香醇和醋酐反应而得

L(-)-葑酮文献

[Chemical composition of essential oil obtained from Romanian fennel fruits].

Rev. Med. Chir. Soc. Med. Nat. Iasi. 115(2) , 590-4, (2011)

For therapeutical purposes, fennel (Foeniculum vulgare Mill.), an important aromatic plant, is used for its expectorant, antispasmodic, carminative and diuretic properties. The chemical composition, e...

Biosynthesis of monoterpenes: conversion of the acyclic precursors geranyl pyrophosphate and neryl pyrophosphate to the rearranged monoterpenes fenchol and fenchone by a soluble enzyme preparation from fennel (Foeniculum vulgare).

Arch. Biochem. Biophys. 200(2) , 524-33, (1980)

Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl).

J. Phys. Chem. A 116(16) , 4097-107, (2012)

Relative kinetic techniques have been used to measure the rate coefficients for the reactions of oxygenated terpenes (menthol, borneol, fenchol, camphor, and fenchone) and cyclohexanol with hydroxyl r...

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