H-LYS-GLN-ALA-GLY-ASP-VAL-OH

H-LYS-GLN-ALA-GLY-ASP-VAL-OH用途

Lys-Gln-Ala-Gly-Asp-Val(KQAGDV)是纤维蛋白原γ链序列中六个最羧基末端的氨基酸。Lys-Gln-Ala-Gly-Asp-Val是一种通过α2bβ3整合素介导的细胞粘附肽。Lys-Gln-Ala-Gly-Asp-Val是平滑肌细胞(SMC)的有效粘附配体[1][2]。

H-LYS-GLN-ALA-GLY-ASP-VAL-OH名称

[ CAS 号 ]:
80755-87-9

[ 中文名 ]:
H-LYS-GLN-ALA-GLY-ASP-VAL-OH

[ 英文名 ]:
H-Lys-Gln-Ala-Gly-Asp-Val-OH

[英文别名 ]:

Lys-Gln-Ala-Gly-Asp-Val
K-Q-A-G-D-V

H-LYS-GLN-ALA-GLY-ASP-VAL-OH生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 炎症/免疫

信号通路 >> 细胞骨架 >> Integrin

[体外研究]

Lys-Gln-Ala-Gly-Asp-Val(2 nM)改善了平滑肌细胞在聚合物上的粘附和生长[2]。

H-LYS-GLN-ALA-GLY-ASP-VAL-OH物理化学性质

[ 分子式 ]:
C₂₅H₄₄N₈O₁₀

[ 分子量 ]:
616.66400

[ 精确质量 ]:
616.31800

[ PSA ]:
315.23000

[ LogP ]:
0.05420

H-LYS-GLN-ALA-GLY-ASP-VAL-OHMSDS

详细MSDS(安全技术说明书)

H-LYS-GLN-ALA-GLY-ASP-VAL-OH安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

H-LYS-GLN-ALA-GLY-ASP-VAL-OH文献

Evaluation of various silicon-and boron-containing compounds for the detection of phosphorylation in peptides via gas-phase ion-molecule reactions.

Eur. J. Mass Spectrom. (Chichester, Eng.) 20(4) , 337-44, (2014)

Gas-phase ion-molecule reactions [IMR] of various boron- and silicon-containing neutrals were investigated as a potential route for detecting phosphorylation within peptides in the negative ion mode. ...

Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds.

J. Biomed. Mater. Res. 60 , 86-93, (2002)

The effects of cell adhesion peptides (RGDS, KQAGDV, VAPG) on vascular smooth muscle cells grown on modified surfaces and in tissue-engineering scaffolds were examined. Cells were more strongly adhere...

Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level.

Br. J. Haematol. 121 , 341-348, (2003)

Polymorphonuclear leucocytes and blood platelets co-operate in several pathophysiological processes, and arachidonic acid (AA) metabolites produced in response to the activation of these cells are pot...

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