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N,N-二甲基-1-萘胺

N,N-二甲基-1-萘胺用途

有机合成中间体

N,N-二甲基-1-萘胺名称

[ CAS 号 ]:
86-56-6

[ 中文名 ]:
N,N-二甲基-1-萘胺

[ 英文名 ]:
N,N-Dimethyl-1-naphthylamine

[中文别名 ]:

[英文别名 ]:

EINECS 201-682-4
N,N-dimethylnaphthalen-1-amine
MFCD00003919

N,N-二甲基-1-萘胺生物活性

[ 描述 ]:

N、 N-二甲基-1-萘胺是芳族胺和染料。N、 N-二甲基-1-萘胺可用于硝酸盐还原试验[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kasali A. Bello, et al. Violet to cyan azo dyes derived from 4-amino-3-nitrobenzaldehyde as diazo component. Dyes and Pigments. 1989, 65-76.

[2]. Tsikas D. Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine/nitric oxide area of research. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 15;851(1-2):51-70.

N,N-二甲基-1-萘胺物理化学性质

[ 密度 ]:
1.042 g/mL at 25 °C(lit.)

[ 沸点 ]:
139-140 °C13 mm Hg(lit.)

[ 分子式 ]:
C₁₂H₁₃N

[ 分子量 ]:
171.23800

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
171.10500

[ PSA ]:
3.24000

[ LogP ]:
2.90580

[ 外观性状 ]:
淡黄色液体

[ 折射率 ]:
n20/D 1.622(lit.)

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
insoluble

N,N-二甲基-1-萘胺MSDS

N,N-二甲基-1-萘胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QM2825000

CHEMICAL NAME :: 1-Naphthylamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 86-56-6

BEILSTEIN REFERENCE NO. :: 1424075

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H13-N

MOLECULAR WEIGHT :: 171.26

WISWESSER LINE NOTATION :: L66J BN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,265,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1111 No. of Facilities: 43 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 383 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1111 No. of Facilities: 150 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2006 (estimated) No. of Female Employees: 1662 (estimated)

N,N-二甲基-1-萘胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R22;R36/37/38;R51/53

[ 安全声明 (欧洲) ]:
S26-S36-S61-S37/39-S29

[ 危险品运输编码 ]:
UN 1369/2810

[ WGK德国 ]:
2

[ RTECS号 ]:
QM2825000

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921450090

N,N-二甲基-1-萘胺合成路线

N,N-二甲基-1-萘胺上下游产品

N,N-二甲基-1-萘胺上游产品

N,N-二甲基-1-萘胺下游产品

N,N-二甲基-1-萘胺海关

[ 海关编码 ]: 2921450090

[ 中文概述 ]:
2921450090. 1-萘胺和2-萘胺的衍生物及盐(包括1-萘胺）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

N,N-二甲基-1-萘胺文献

Slow Relaxation of Shape and Orientational Texture in Membrane Gel Domains.

Langmuir 31 , 12699-707, (2015)

Gel domains in lipid bilayers are structurally more complex than fluid domains. Growth dynamics can lead to noncircular domains with a heterogeneous orientational texture. Most model membrane studies ...

Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4.

Biochim. Biophys. Acta 1841(12) , 1716-24, (2015)

Human apolipoprotein E (apoE) isoforms exhibit different conformational stabilities and lipid-binding properties that give rise to altered cholesterol metabolism among the isoforms. Using Trp-substitu...

Detection of bacterial nitrate reductase activity by the use of a powdered reagent and rapid swab methods as compared to the conventional test.

Zentralbl. Bakteriol. 279(2) , 225-30, (1993)

A rapid swab method using either a dry or moist swab soaked with potassium nitrate/benzalkonium chloride solution, and a method employing a single powdered reagent were assessed as possible alternativ...

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