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H-精氨酸-甘氨酸-天冬氨酸-丝氨酸-脯氨酸-丙氨酸-丝氨酸-丝氨酸-赖氨酸-脯氨酸-OH

用途

RGDSPASSKP 是一种含有 RGDS 的纤连蛋白十肽。

名称

[ CAS 号 ]:
91575-25-6

[ 中文名 ]:
H-精氨酸-甘氨酸-天冬氨酸-丝氨酸-脯氨酸-丙氨酸-丝氨酸-丝氨酸-赖氨酸-脯氨酸-OH

[ 英文名 ]:
H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH acetate salt

[中文别名 ]:

[英文别名 ]:

arg-gly-asp-ser-pro-ala-ser-ser-lys-pro
h-arg-gly-asp-ser-pro-ala-ser-ser-lys-pro-oh
rgdspasskp

生物活性

[ 描述 ]:

RGDSPASSKP 是一种含有 RGDS 的纤连蛋白十肽。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 细胞骨架 >> Integrin

[参考文献]

[1]. Soteriadou KP, et al. The Ser-Arg-Tyr-Asp region of the major surface glycoprotein of Leishmania mimics the Arg-Gly-Asp-Ser cell attachment region of fibronectin. J Biol Chem. 1992 Jul 15;267(20):13980-5.

物理化学性质

[ 密度 ]:
1.61g/cm3

[ 分子式 ]:
C₄₀H₆₈N₁₄O₁₆

[ 分子量 ]:
1001.05000

[ 精确质量 ]:
1000.49000

[ PSA ]:
493.55000

[ 折射率 ]:
1.686

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Fibrinogen mitogenic effect on hemopoietic cell lines: control via receptor modulation.

Proc. Natl. Acad. Sci. U. S. A. 83 , 6494, (1986)

The possibility that the mitogenic effect of fibrinogen, a major plasma protein (3 mg/ml), is mediated by specific membrane receptors was studied. Specific binding analysis showed that fibrinogen rece...

Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function.

J. Cell Biol. 99 , 29, (1984)

Fibronectin and certain polypeptide regions of this adhesive glycoprotein mediate cell attachment and spreading on various substrates. We explored the theoretical prediction that this adhesive protein...

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