四氢糠醇

四氢糠醇用途

【用途一】
用作溶剂，也用作制取二氢呋喃、赖氨酸等的原料，其酯类用作增塑剂
【用途二】
用作溶剂，也用于橡胶、染料工业
【用途三】
GB 2760--1996规定为允许使用的食用香料。
【用途四】
用于制备丁二酸、戊二醇、四氢呋喃、吡喃等，也用作涂料、树脂和油脂的溶剂。在印染工业中用作润滑剂、分散剂，药品的脱色、脱臭剂，还用作增塑剂、除草剂、杀虫剂等有机合成的原料。四氢糠醇溴化得到四氢呋喃甲基溴，经硫代硫酸钠置换制得四氢呋喃甲基硫代硫酸钠。是长效维生素B1（呋喃硫胺）的原料。
【用途五】
树脂和油类的溶剂。染料和橡胶的氧化。制造酯类。明胶溶液稳定剂。印染工业润湿剂。分散剂。某些药物的脱色除臭剂。

四氢糠醇名称

[ CAS 号 ]:
97-99-4

[ 中文名 ]:
四氢糠醇

[ 英文名 ]:
Tetrahydrofurfuryl alcohol

[中文别名 ]:

[英文别名 ]:

2-Furanmethanol, tetrahydro-
(Tetrahydrofuran-2-yl)methanol
Tetrahydrofuran-2-ylmethanol
EINECS 202-625-6
MFCD00005372
THFA
Tetrahydro-2-furanylmethanol
Tetrahydrofurfuryl alcohol
2-Furanmethanol,tetrahydro-
T5OTJ B1Q

四氢糠醇物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
176.8±8.0 °C at 760 mmHg

[ 熔点 ]:
-80ºC

[ 分子式 ]:
C₅H₁₀O₂

[ 分子量 ]:
102.132

[ 闪点 ]:
83.9±0.0 °C

[ 精确质量 ]:
102.068077

[ PSA ]:
29.46000

[ LogP ]:
-0.39

[ 外观性状 ]:
无色至淡黄色液体

[ 蒸汽密度 ]:
3.52 (vs air)

[ 蒸汽压 ]:
0.3±0.7 mmHg at 25°C

[ 折射率 ]:
1.447

[ 储存条件 ]:
包装完整、轻装轻放,库房通风、远离明火、高温、与氧化剂分开存放

[ 水溶解性 ]:
soluble

四氢糠醇MSDS

详细MSDS(安全技术说明书)

四氢糠醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU2450000

CHEMICAL NAME :: 2-Furanmethanol, tetrahydro-

CAS REGISTRY NUMBER :: 97-99-4

BEILSTEIN REFERENCE NO. :: 0102723

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C5-H10-O2

MOLECULAR WEIGHT :: 102.15

WISWESSER LINE NOTATION :: T5OTJ B1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,786,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4658,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4658,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 32(2),273,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 725 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 8,294,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4658,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4658,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4658,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83085 No. of Facilities: 1654 (estimated) No. of Industries: 9 No. of Occupations: 9 No. of Employees: 2169 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83085 No. of Facilities: 5004 (estimated) No. of Industries: 41 No. of Occupations: 33 No. of Employees: 81543 (estimated) No. of Female Employees: 48075 (estimated)

四氢糠醇安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H319-H360Df

[ 警示性声明 ]:
P201-P280-P305 + P351 + P338-P308 + P313-P337 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S39

[ 危险品运输编码 ]:
NA 1993 / PGIII

[ WGK德国 ]:
2

[ RTECS号 ]:
LU2450000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
29321300

四氢糠醇合成路线

详细合成路线

四氢糠醇上下游产品

四氢糠醇上游产品

四氢糠醇下游产品

四氢糠醇制备

1.由糠醛加氢制得。当采用镍-铬-铜系催化剂时，反应温度为170-180℃，压力为7.5-10.5MPa。由糠醛在催化剂Ni存在下，用170～180℃、7.355～7.845MPa下，连续加压氢化而得。

精制方法：分馏精制。

2.烟草：FC，9， 18。

四氢糠醇海关

[ 海关编码 ]: 2932130000

[ 中文概述 ]:
HS: 2932130000. 糠醇及四氢糠醇. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最低关税:6.0%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS: 2932130000. (tetrahydrofuran-2-yl)methanol. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:6.0%. general tariff:20.0%

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